Mccune Albright Syndrome is a disease caused by a single mutation in an individual's gene—this means that the disease is not inherited but, rather, occurs when the child is developing in the womb. Characterized by very premature puberty in girls (some children may have an onset of menses as young as four or five month of age). In boys, puberty may also be premature but this is not as common in boys as the phenomenon is in girls.
Removal of the adrenal glands can sometimes halt the disease by reducing the amount of hormones which course through the body. Unfortunately though, there is no known cure for the disease.
There is no prevention for Mccune Albright Syndrome, but the good news is that people born with Mccune Albright Syndrome live relatively normal lives. There are, however, some challenging side effects that come along with the disease – a few of which are documented below.
The most noticeable sign that a child may have Mccune Albright Syndrome is a cafe-au-lait speckled back. Cafe-au-lait spots are brown in color and generally have irregular edges. For some reason, the discolored skin tends to occur most frequently on the back. However, patients with the disease may also have brown spots on the face or torso or, less frequently on the legs.
Although discolored skin is the most common symptom of Mccune Albright Syndrome, there are more severe symptoms that are associated with the disease. Such symptoms include blindness, deformities in the face from abnormal bone development, and frequent bone fractions. and gigantism. Individuals with the disease may grown abnormally tall and heavy and develop very quickly into puberty.
Along with the common symptoms of Mccune Albright Syndrome, there are other less common side effects. Side effects include blindness and/or deafness, and, even less rare, tumors of the bone. Another less common side effect is that bones may turn soft and more porous—a condition called Osteitis fibrosa cystica.
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