Zofran Side Effects

For cancer patients that are going to be treated with either chemotherapy or surgery, it can be helpful to be aware of all of the Zofran side effects. Zofran (known generically as ondansetron) is a medication that is commonly used to halt or decrease uncomfortable side effects that can occur due to cancer medication (radiation and chemotherapy) or surgery. The medicine operates by obstructing the functions of chemicals that can lead to throwing up and feelings of nausea.

  1. Side effects that most frequently occur as a result of Zofran include headache, exhaustion, sleepiness, weakness, fever, decreased levels of oxygen, agitation, nervousness, dizziness, lightheadedness, itchiness and urinary retention. In general, these Zofran side effects are not considered to be serious and tend to subside with some time.
  2. In some instances, more severe side effects that occur with Zofran. The more serious possible Zofran effects include feelings of faintness, temporary loss of vision, vision disturbances (such as blurriness), chest ache, having a hard time swallowing, shivering, tremors, shaky movements, abnormal rashes on the skin, wheezing, swelling, breaking out into hives, difficulty breathing (including being short of breath), reduced heart rate and complete lack of urination. It is necessary to seek medical attention as soon as possible if any of these side effects start to happen.
  3. Zofran also can lead to some very rare side effects. Some less common side effects of the medicine are hiccups, facial redness, rapid heart rate (tachycardia), abnormally rigid muscles, elevated levels of liver enzymes (which can appear during examinations), heart rhythm changes and temporary blindness. Since these side effects are rather uncommon, it can be helpful to consult your doctor about them.
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